Aortic aneurysm and dissection
How the elastic wall of the aorta weakens, why a weakened segment balloons and keeps growing until it may rupture, and how a tear in the inner wall lets blood split the layers apart in an aortic dissection.
By the end, you can
- Describe the aorta’s course and the structure of its wall.
- Explain how degeneration of the media weakens the aortic wall and lets it dilate.
- Use the law of Laplace to explain why aneurysms tend to grow faster as they enlarge.
- Explain how an intimal tear produces a dissection with a false lumen.
- Relate the symptoms of rupture and dissection to blood loss and branch artery occlusion.
- Recognise the classic appearances, classifications and tests of aortic aneurysm and dissection, and explain how blood-pressure control and repair act on the mechanism.
What it is
An aortic aneurysm is a permanent, localised dilatation of the aorta, conventionally to at least 1.5 times its normal diameter (for the abdominal aorta, 3 cm or more). An aortic dissection is a tear in the aorta’s inner layer that lets blood track between the layers of its wall, creating a second, false channel. Both can rupture and are medical emergencies when they do.
3 types to tell apart
- Abdominal aortic aneurysm
- The commonest aneurysm, usually below the renal arteries; linked to age, smoking, male sex and family history.
- Thoracic aortic aneurysm
- Often in the ascending aorta; linked to hypertension, a bicuspid aortic valve and inherited connective tissue disorders.
- Dissection: ascending (type A) and descending (type B)
- Dissections involving the ascending aorta are the most immediately dangerous; those confined to the descending aorta behave differently.
US spelling: fibres → fibers.
Normal function
The aorta and its elastic wall
The aorta leaves the left ventricle as the , arches over the heart (the , giving off the branches to the head and arms) and descends through the chest as the , continuing through the abdomen to divide into the iliac arteries.
Its wall has three layers, like other arteries: a thin intima, a thick media and an outer adventitia. Unlike a muscular artery, the aortic media is packed with dozens of layers of elastic fibres with smooth muscle and collagen between them.
With each heartbeat the elastic wall stretches to absorb the surge of blood, then recoils to keep blood flowing in diastole. Collagen sets the wall’s ultimate strength, stopping it from stretching too far.
Underlying change · Step 1 of 4
The media degenerates and the wall weakens
The full lesson is part of Student Pro
It takes you through all 4 steps of the mechanism, explains the symptoms, signs and findings each step causes, adds the exam detail and how treatment works where the lesson has them, then recaps it and lets you check yourself with 10 self-check questions. The full pathophysiology library: guided lessons with self-check questions comes with Student Pro, with 100 tutor answers a month and the full available catalogue.
Free to read: the introduction and .
Disrupted function · Step 2 of 4
Why an aneurysm keeps growing
The full lesson is part of Student Pro
It takes you through all 4 steps of the mechanism, explains the symptoms, signs and findings each step causes, adds the exam detail and how treatment works where the lesson has them, then recaps it and lets you check yourself with 10 self-check questions. The full pathophysiology library: guided lessons with self-check questions comes with Student Pro, with 100 tutor answers a month and the full available catalogue.
Free to read: the introduction and .
Disrupted function · Step 3 of 4
Dissection: blood splits the wall
The full lesson is part of Student Pro
It takes you through all 4 steps of the mechanism, explains the symptoms, signs and findings each step causes, adds the exam detail and how treatment works where the lesson has them, then recaps it and lets you check yourself with 10 self-check questions. The full pathophysiology library: guided lessons with self-check questions comes with Student Pro, with 100 tutor answers a month and the full available catalogue.
Free to read: the introduction and .
Consequences · Step 4 of 4
Rupture and its consequences
The full lesson is part of Student Pro
It takes you through all 4 steps of the mechanism, explains the symptoms, signs and findings each step causes, adds the exam detail and how treatment works where the lesson has them, then recaps it and lets you check yourself with 10 self-check questions. The full pathophysiology library: guided lessons with self-check questions comes with Student Pro, with 100 tutor answers a month and the full available catalogue.
Free to read: the introduction and .
Symptoms and signs
Symptoms, signs and findings
The full lesson is part of Student Pro
It takes you through all 4 steps of the mechanism, explains the symptoms, signs and findings each step causes, adds the exam detail and how treatment works where the lesson has them, then recaps it and lets you check yourself with 10 self-check questions. The full pathophysiology library: guided lessons with self-check questions comes with Student Pro, with 100 tutor answers a month and the full available catalogue.
Free to read: the introduction and .
Exam detail
Exam detail
The full lesson is part of Student Pro
It takes you through all 4 steps of the mechanism, explains the symptoms, signs and findings each step causes, adds the exam detail and how treatment works where the lesson has them, then recaps it and lets you check yourself with 10 self-check questions. The full pathophysiology library: guided lessons with self-check questions comes with Student Pro, with 100 tutor answers a month and the full available catalogue.
Free to read: the introduction and .
Treatment
How treatment works
The full lesson is part of Student Pro
It takes you through all 4 steps of the mechanism, explains the symptoms, signs and findings each step causes, adds the exam detail and how treatment works where the lesson has them, then recaps it and lets you check yourself with 10 self-check questions. The full pathophysiology library: guided lessons with self-check questions comes with Student Pro, with 100 tutor answers a month and the full available catalogue.
Free to read: the introduction and .
Recap
Recap
The full lesson is part of Student Pro
It takes you through all 4 steps of the mechanism, explains the symptoms, signs and findings each step causes, adds the exam detail and how treatment works where the lesson has them, then recaps it and lets you check yourself with 10 self-check questions. The full pathophysiology library: guided lessons with self-check questions comes with Student Pro, with 100 tutor answers a month and the full available catalogue.
Free to read: the introduction and .
Self-check
Check your understanding
The full lesson is part of Student Pro
It takes you through all 4 steps of the mechanism, explains the symptoms, signs and findings each step causes, adds the exam detail and how treatment works where the lesson has them, then recaps it and lets you check yourself with 10 self-check questions. The full pathophysiology library: guided lessons with self-check questions comes with Student Pro, with 100 tutor answers a month and the full available catalogue.
Free to read: the introduction and .